منابع مشابه
Museum samples reveal rapid evolution by wild honey bees exposed to a novel parasite
Understanding genetic changes caused by novel pathogens and parasites can reveal mechanisms of adaptation and genetic robustness. Using whole-genome sequencing of museum and modern specimens, we describe the genomic changes in a wild population of honey bees in North America following the introduction of the ectoparasitic mite, Varroa destructor. Even though colony density in the study populati...
متن کاملCo-infections determine patterns of mortality in a population exposed to parasite infection
Many individual hosts are infected with multiple parasite species, and this may increase or decrease the pathogenicity of the infections. This phenomenon is termed heterologous reactivity and is potentially an important determinant of both patterns of morbidity and mortality and of the impact of disease control measures at the population level. Using infections with Theileria parva (a tick-born...
متن کاملUncoupling of induced protein processing from maturation in dendritic cells exposed to a highly antigenic preparation from a helminth parasite.
TLR ligands induce dendritic cell (DC) maturation. During this process, cells initiate proteolytic degradation of internalized protein Ags into peptides that complex with MHC class II (MHC II) and simultaneously increase expression of costimulatory molecules and of cytokines such as IL-6, IL-12, and IL-23. In these ways, TLR-activated DCs are able to activate naive Th cells and initiate Th1 and...
متن کاملPraziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens.
BACKGROUND Schistosomiasis is a major parasitic disease affecting >200 million people in the developing world, and 400 million people are at risk for infection. This study aimed to identify and compare proteins recognized by serum samples from schistosome-exposed individuals before and after curative praziquantel treatment. METHODS Proteins recognized by pooled serum samples from Schistosoma ...
متن کاملCo-infections determine patterns of mortality in populations exposed to parasite infection
Citation for published version: Woolhouse, MEJ, Thumbi, SM, Jennings, A, Chase-Topping, M, Callaby, R, Kiara, H, Oosthuizen, MC, Mbole-Kariuki, MN, Conradie, I, Handel, IG, Poole, EJ, Njiiri, E, Collins, NE, Murray, G, Tapio, M, Auguet, OT, Weir, W, Morrison, WI, Kruuk, LEB, Bronsvoort, BMDC, Hanotte, O, Coetzer, K & Toye, PG 2015, 'Coinfections determine patterns of mortality in populations ex...
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ژورنال
عنوان ژورنال: Nature
سال: 1988
ISSN: 0028-0836,1476-4687
DOI: 10.1038/336120a0